Massallah regarding inheritance

Dear mufti saab
as sallaam ualaikum
my father has 5 brothers and 5 sisters , 3 sisters passed on . my grandfather and his sons ran a business for many years ,some brothers were active in the business and some were not.the property was built by my grand father should this property be divided?
2. one sister was not married and has no children , what happens in this case?

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